Bioinformatics

De ontwikkeling van steeds nieuwe en betere high-throughput assay technologieën transformeert de moleculaire biologie in een razendsnel tempo. Sequencing van volledige genomen en de mogelijkheid om RNA, eiwitten, metabolieten en hun interacties op grote schaal (genoom-breed) te meten brengen een revolutie teweeg in biologisch onderzoek en dientengevolge ook op de diagnostiek. Voor het eerst komen

Transitions, Innovation en Governance

TRIG provides an overview of frameworks and methods to study and guide sustainable innovation, sustainability transitions, in particular socio-technical transitions and their governance, as these are all important to bring about sustainability and transitions to sustainability. Increasing the understanding of the underlying societal mechanisms and processes of sustainable innovation and sustainability transitions is important in

Data Mining

The goal of the course is to teach students how to think like a data miner. Intuitively, this means you have the mindset and skills to find practical solutions to common problems you encounter when extracting knowledge, patterns, and models from large data sets. To make such solutions effective, you must understand both the underlying

Microbial Genomics

Microbes (bacteria, archaea and microbial eukaryotes, including fungi) are key members of our biosphere and are highly relevant for human life as mutualists and pathogens and as crucial drivers of nutrient cycling, agriculture, and many other aspects of our daily lives. The genomes of microbes provide a wealth of information on the processes and mechanisms

Advanced Bioinformatics (UU)

In de cursus wordt aandacht besteed aan het begrijpen van en werken met grote hoeveelheden gegevens zoals de laatste jaren in veel genetisch en moleculair onderzoek worden verkregen. Deze technologische ontwikkelingen vereisen nieuwe vaardigheden en concepten om life science onderzoek te kunnen begrijpen en uitvoeren. In het eerste deel van de cursus wordt een veel

Advanced Cellular Imaging Techniques

Advanced light microscopy and reporter gene techniques are indispensable for mechanistic studies on the functioning and organization of cells. New microscopy technologies and digital imaging allow us to study dynamic processes at shorter time scales and with higher spatial resolution in living cells. In this practical course the principles and cell biological application of different

Molecular genetic research techniques

In deze voornamelijk praktische cursus leren jullie hoe je experimenteel processen in levende bacteriën, gisten, planten en zoogdiercellen kunt bestuderen, en de moleculair-genetische technieken die hiervoor worden toegepast. De technieken die jullie gaan leren en toepassen variëren van basale tot geavanceerde recombinante DNA-technieken, zoals: overdracht van genetisch materiaal tussen bacteriën, genetische mapping in planten, yeast-2-hybrid

Modelling biological systems

Biological systems are arguably the most complex systems science tries to understand. We make observations, and try to obtain useful insight in the systems. This requires hypotheses; ideas of how we believe the world around us is structured and operates. Models translate our hypotheses into concrete predictions about our objects of study that can be

Ecogenomics

The field of ecological genomics strives to uncover the genetic and molecular mechanisms influencing responses and adaptations of organisms to their environment. Achieving this aim requires insight in evolution and selection pressure and how that results in natural variation. Using this natural variation to study mechanisms requires a good understanding of both ecologically important phenotypes