In the course Digital Innovation we focus on the role of Information and Communication Technology (ICT) in the fundamental transformations of industries and societies. After introducing the nature of ICTs, the first part of the course starts by providing an historical and theoretical introduction to digital innovation from a societal perspective. Specific emphasis is on the economic and social effects of digitalisation. The course then goes into recent developments brought about by digital platforms and artificial intelligence. Throughout the course, attention is paid to the role of digital innovation in specific domains such as health and mobility. In the second part of the course students apply their knowledge to a case in a domain of their choice.