This course covers the process of bioinformatics data analysis and the interpretation of the results in a biological context. The following topics will be addressed in the course: command line usage, programming/scripting, current bioinformatics data analysis tools, and automated analysis pipelines. The first part of the course will cover command line usage (linux), bioinformatics script programming (python), as well as the theory and tools required to analyse data produced by current sequencing technologies and interpret the results. Topics include genome assembly, sequence annotation, gene expression, biological networks, and comparative genomics. During the second part of the course, students – in teams – will apply their knowledge in a small research project. Given a specific biological question and the required data, the goal is to build a data analysis pipeline and describe the biological interpretation.